Refugio County is a county located in the U.S. state of Texas. As of the 2010 census, the population was 7,383. Its county seat is Refugio. The county was created as a municipality of Mexico in 1834 and organized as a county in 1837.GeographyAccording to the U.S. Census Bureau, the county has a total area of, of which is land and (5.8%) is water.Major highways20px U.S. Highway 7725px Interstate 69E is currently under construction and will follow the current route of U.S. 77 in most places.20px State Highway 3520px State Highway 23920px Farm to Market Road 13620px Farm to Market Road 77420px Farm to Market Road 244120px Farm to Market Road 2678