First Friday 6 -10 pm and the following Saturday 11am to 4pm each month in the River District Downtown Fort Myers comes alive ARTistically! Celebrate the Arts with exciting new opening exhibits at 14 galleries! Meet the Artists! Live Art Demos! Friday nights First Street is closed to automobiles - Art Vendors on First Street! Saturday Afternoons First Street is open to automobiles - Art Vendors may be in front of the galleries. Eat, Shop or just enjoy the Atmosphere! Rain or Shine!