JoVE was established as a new tool in life science publication and communication, with participation of scientists from leading research institutions. JoVE takes advantage of video technology to capture and transmit the multiple facets and intricacies of life science research. Visualization greatly facilitates the understanding and efficient reproduction of both basic and complex experimental techniques, thereby addressing two of the biggest challenges faced by today’s physical, medical, and life science research community: i) low transparency and poor reproducibility of experiments and ii) time and labor-intensive nature of learning new experimental techniques.