The artist began experimenting on mosaic from found materials such as marble, pebbles, river rocks and natural stones. In 2011, she went to the Chicago Mosaic School learning the Italian Byzantine mosaic art using the traditional hammer and hardie. In 2014, she diversified her art at the Institute of Mosaic Art in Berkeley under Rachel Rodi. Maria Isabel Lopez is a professional member of SAMA-Society of American Mosaic Artists.