Lake Mendota is easily accessible from many routes.
Lake Mendota is located right off of Route 52/251. If you are coming from the Chicagoland area or Northern Suburbs, use I-294 south or I-355 south to I-88 west, then to I-39 south. Also from Chicago, I-55 south to I-80 west may be used to reach I-39 north. If you are coming from the western suburbs, use I-88 west to I-39 south. If you live in the Southern Suburbs, take I-80 west to I-39 north. The exit off I-39 for Mendota is exit #72, Route 34, Mendota-Earlville, turn west on Route 34 and in 2 miles you will be in Mendota. From other areas, north or south of Mendota, use I-39, U.S. Route 52 or U.S. Route 251. For visitors from the east or west of Mendota, use I-80 to I-39 north or U.S. Route 34.