Misty Vale, also known as the G. W. Karsner House, is a historic home located near Odessa, New Castle County, Delaware. It was built about 1850, and is a 2 1/2-story, five-bay frame, cross-gable roof house built in a vernacular Victorian style. It has a frame, three-bay, gable-roofed wing, a hipped-roof, frame addition to the east and an enclosed porch. Also on the property are a square, 1 1/2-story, hipped roof, drive-through granary with a cupola on top and two barns.It was listed on the National Register of Historic Places in 1985.