Located in the center of New York State, Onondaga County is home to the city of Syracuse. We are within 350 miles of all major cities in the Northeast, conveniently situated at the intersection of Interstate Highways 81 and 90 (NYS Thruway). Local Amtrak and Greyhound terminals are located in our new Regional Transportation Center. Arriving by air brings you in to the newly remodeled Hancock International Airport, while the New York State Barge Canal System provides local connection by boat to the Great Lakes and the St. Lawrence River.