Pueblo County is one of the 64 counties in the U.S. state of Colorado. As of the 2010 census, the population was 159,063. The county seat is Pueblo. The county was named for the historic city of Pueblo which took its name from the Spanish language word meaning "town" or "village".Pueblo County comprises the Pueblo, CO Metropolitan Statistical Area.GeographyAccording to the U.S. Census Bureau, the county has a total area of, of which is land and (0.5%) is water.Adjacent countiesEl Paso County - northLincoln County - northeastCrowley County - eastOtero County - eastLas Animas County - southHuerfano County - southwestCuster County - westFremont County - northwestNational protected areasSan Isabel National ForestGreenhorn Mountain Wilderness