Recursion Pharmaceuticals

Our dynamic team combines innovative biological science with advanced computational algorithms to discover new therapeutic opportunities for rare genetic diseases.

We use high-throughput genetic manipulation to model many diseases in multiple human cell types quickly and efficiently. Thousands of cells representing each model are imaged using high-throughput automated microscopy.

We use automated image segmentation systems to quantify hundreds or thousands of structural relationships in tens of thousands of cells for every disease we model. Our proprietary informatics approaches enable us to identify the critical disease-specific changes associated with each disease model.

Once we have quantified the phenotypic fingerprint (phenoprint) for a disease, we model it en-masse in thousands of wells and evaluate the ability of thousands of drugs to rescue the disease-specific structural perturbations back to 'health'.