Established in 1969 by philanthropist Sam Regenstrief on the Indiana University - Purdue University Indianapolis campus, the Institute is supported by the Regenstrief Foundation and closely affiliated with the Indiana University School of Medicine and the Health and Hospital Corporation of Marion County, Indiana.
Regenstrief receives $3 million per year in core support from the Regenstrief Foundation and has an annual operating budget of approximately $23 million derived from grants and contracts from the National Institutes of Health, the Agency for Healthcare Research and Quality, the Centers for Disease Control and Prevention, national philanthropies, Indianapolis healthcare institutions, and others.
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