San Isidro Mission Cafe was established in 2000 on Westside Rd off of Art Craft Road. In 2012, the restaurant moved to its current location on Country Club Road in River Run Plaza. In the Fall of 2012, Jesus & Julie Cabrales became the new owners. San Isidro Mission Cafe is not only known for its great Mexican food but also for its family friendly service. Daily specials Monday thru Friday. Menudo on Saturdays and Sundays. Caldo de Res, Monday thru Friday. Great Seafood and Healthy Salads available everyday.