Sixth Avenue Bistro is a Cajun/Creole restaurant that is located in Downtown, San Diego. The bistro was 10 news A-list winner for best cajun/creole restaurant. We offer breakfast, lunch and dinner. Our happy hour is from 3:00pm-9:00pm, Monday through Friday. We walking distance from Symphony, Civic Center, and House of Blues and neighbor Cortez Hill, Banker's Hill, Golden Hills, and South Park.