Winston County is a county located in the U.S. state of Mississippi. In the 2010 census, the population was 19,198. Its county seat is Louisville. The county is named for Louis Winston (1784–1824), a colonel in the militia, a prominent lawyer, and a judge of the Mississippi Supreme Court.The county is the site of Nanih Waiya, an ancient mound built in the Woodland period, about 1 CE-300 CE. Since the 17th century, it has been venerated by the Choctaw people who later occupied the area. As of 2008, the mound is owned by the Mississippi Band of Choctaw Indians, a Federally-recognized tribe.GeographyAccording to the U.S. Census Bureau, the county has a total area of, of which is land and (0.5%) is water.Major highways20px Mississippi Highway 1420px Mississippi Highway 1520px Mississippi Highway 1920px Mississippi Highway 25